It's the battle of the saints at McDiarmid Park as St Mirren visit St Johnstone with the Perth side aiming for a second successive Scottish Cup semi-final berth.
And in Dumfries, it's the all First Division clash between Queen of the South and Dundee at Palmerston Park.
St Johnstone v St Mirren: Commentary from John Barnes, Murdo MacLeod, Allan Preston and Chick Young.
After all the action on the park, the semi-final draw will follow at 1705GMT, conducted by Fifa president Sepp Blatter and his Uefa counterpart Michel Platini, live at Gleneagles.
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